National Immunization Schedule 

Vaccine 

When to give 

Dose 

Route

Site

For Infants 

BCG 

At birth or as early as possible till one year of age 

0.1ml  (0.05ml until 1 month of age) 

Intra -dermal

Left Upper Arm

Hepatitis B Birth dose 

At birth or as early as possible within 24 hours 

0.5 ml 

Intramuscular

Anterolateral side of mid thigh-LEFT

OPV Birth dose 

At birth or as early as possible within the first 15 days 

2 drops 

Oral

-

OPV 1,2 & 3 

 At 6 weeks, 10 weeks & 14 weeks 

2 drops 

Oral

-

IPV (inactivated Polio Vaccine)

 14 weeks 

0.5 ml 

Intramuscular

Anterolateral side of mid thigh-RIGHT

Pentavelant  1,2 & 3 

 At 6 weeks, 10 weeks & 14 weeks 

0.5 ml 

Intramuscular

Anterolateral side of mid thigh-LEFT

Rota Virus Vaccine

 At 6 weeks, 10 weeks & 14 weeks 

5 drops 

Oral

-

Measles 1^st Dose 

9 completed months-12 months. (give up to 5 years if not received at 9-12 months age) 

0.5 ml 

Subcutaneous

Right Upper Arm

Vitamin A, 1^st Dose 

At 9 months with measles 

1 ml  (1 lakh IU) 

Oral

-

For children

DPT 1^st  booster 

16-24 months 

0.5 ml 

Intramuscular

Anterolateral side of mid thigh-LEFT

OPV Booster 

16-24 months 

2 drops 

Oral

Measles 2^nd  dose 

16-24 Months 

0.5 ml 

Subcutaneous

Right Upper Arm

Vitamin A  (2^nd to 9^th dose) 

16 months with DPT/OPV booster, then, one dose every 6 month up to the age of 5 years) 

2 ml  (2 lakh IU) 

Oral

-

DPT 2^nd Booster 

5-6 years 

0.5 ml. 

Intramuscular

Left Upper Arm

TT 

10 years & 16 years 

0.5 ml 

Intramuscular

Upper Arm

Age (completed wks/mo/y)

Vaccines

Comments

Birth

BCG

Administer these vaccines to all newborns before hospital discharge

OPV 0

Hep-B 1

6 weeks

DTwP 1

DTP:

IPV 1

• DTaP vaccine/combinations should preferably be avoided for the primary series

Hep-B 2
Hib 1

• DTaP vaccine/combinations should be preferred in  certain specific circumstances/conditions only

Rotavirus 1

PCV 1

• No need of repeating/giving additional doses of whole-cell pertussis (wP) vaccine to a child who has earlier completed their primary schedule with acellular pertussis (aP) vaccine-containing products

Polio:

• All doses of IPV may be replaced with OPV if administration of the former is not feasible

• Additional doses of OPV on all supplementary immunization activities (SIAs)

• Two doses of IPV instead of 3 for primary series if started at 8 weeks, and 8 weeks interval between the doses

• No child should leave the facility without polio immunization (IPV or OPV), if indicated by the schedule

Rotavirus: 

• 2 doses of RV1 and 3 doses of RV5

• RV1 should be employed in 10 and 14 week schedule, instead of  6 and 10 week

• 10 and 14 week schedule of RV1 is found to be far more immunogenic than existing 6 and 10 week schedule

10 weeks

DTwP 2

Rotavirus:

IPV 2

• If RV1 is chosen, the first dose should be given at 10 weeks

Hib 2

Rotavirus 2

PCV 2

14 weeks

DTwP 3

Rotavirus:

IPV 3

• Only 2 doses of RV1 are recommended at present

Hib 3

• If RV1 is chosen, the 2nd dose should be given at 14 weeks

Rotavirus 3

PCV 3

6 months

OPV 1

Hepatitis-B:

Hep-B 3

• The final (third or fourth) dose in the HepB vaccine series should be administered no earlier than age 24 weeks and at least 16 weeks after the first dose

9 months

OPV 2

MMR:

MMR-1

• Measles-containing vaccine ideally should not be administered before completing 270 days or 9 months of life

• The 2nd dose must follow in 2nd year of life

• No need to give stand-alone measles vaccine

Typhoid:

9-12 months

Typhoid Conjugate Vaccine

• Currently, two typhoid conjugate vaccines, Typbar-TCV and PedaTyph available in Indian market

• PedaTyph is not yet approved; the recommendation is  applicable to Typbar-TCV only

• An interval of at least 4 weeks with the MMR vaccine should be maintained while administering this vaccine

• Should follow a booster at 2 years of age

12 months

Hep-A 1

Hepatitis A:

• Single dose for live attenuated H2-strain Hep-A vaccine

• Two doses for all killed Hep-A vaccines are recommended now

15 months

MMR 2

MMR:

Varicella 1

• The 2nd dose must follow in 2nd year of life

PCV booster

• However, it can be given at anytime 4-8 weeks after the 1st dose during 2nd year

16 to 18 months

DTwP B1/DTaP B1

Varicella:

IPV B1, Hib B1

• The risk of breakthrough varicella is lower if given 15 months onwards

• The first booster (4th dose) may be administered as early as age 12 months, provided at least 6 months have elapsed since the third dose.

DTP:

• First and second boosters should preferably be of DTwP

• Considering a higher reactogenicity of DTwP, DTaP can be considered for the boosters

18 months

Hep-A 2

• 2nd dose for killed vaccines; only single dose for live attenuated H2- strain vaccine

2 years

Typhoid booster

• Either Typbar-TCV® or Vi-polysaccharide (Vi-PS) can be employed as booster;

• Typhoid revaccination every 3 years, if Vi-polysaccharide vaccine is used

• Need of revaccination following a booster of Typbar-TCV® not yet determined

4  to 6 years

DTwP B2/DTaP B2

Varicella:

OPV 3 Varicella 2

• 2nd dose can be given at anytime 3 months after the 1st dose

Typhoid booster

10 to 12 years

Tdap/Td

Tdap:

HPV

• Tdap is preferred to Td followed by Td every 10 years

HPV:

• Only 2 doses of either of the two HPV vaccines for adolescent/pre-adolescent girls aged 9-14 years

• For girls 15 years and older, and immunocompromised individuals 3 doses are recommended

• For two-dose schedule, the minimum interval between doses should be 6 months.

• For 3 dose schedule, the doses can be administered at 0, 1-2 (depending on brands) and 6 months

II. IAP recommended vaccines for High-risk* children (Vaccines under special circumstances)

1-Influenza Vaccine

2-Meningococcal Vaccine

3-Japanese Encephalitis Vaccine

4-Cholera Vaccine

5-Rabies Vaccine

6-Yellow Fever Vaccine

7-Pneumococcal Polysaccharide vaccine (PPSV 23)

* High-risk category of children:  Congenital or acquired immunodeficiency (including HIV infection); Chronic cardiac, pulmonary (including asthma if treated with prolonged high-dose oral corticosteroids), hematologic, renal (including nephrotic syndrome) and liver disease; Children on long term steroids, salicylates, immunosuppressive or radiation therapy; Diabetes mellitus, Cerebrospinal fluid leak, Cochlear implant, Malignancies; Children with functional/ anatomic asplenia/ hyposplenia; During disease outbreaks; Laboratory personnel and healthcare workers; Travelers; Children having pets in home; Children perceived with higher threat of being bitten by dogs such as hostellers, risk of stray dog menace while going outdoor.